An agent for preventing and/or treating multiple organ failure

Details An agent for preventing and/or treating multiple organ failure An agent for preventing and/or treating multiple organ failure

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2252711

Preventives and/or remedies for multiple organ failure containing as the active ingredient tumor cytotoxic factor-II (TCF-II) or hepatocyte growth factor (HGF). These drugs are useful in preventing and/or treating deterioration in the general status due to burn, disseminated intravascular coagulation (DIC), circularity failure, hemorrhagis shock, infectious diseases, acute pancreatitis, ischemic injury, hepatorenal syndrome, hemorrhage of digestive tract, nutritional metabolic failure, cancer at the terminal stage, acquired immunodeficiency syndrome (AIDS), radiation injury, etc. and the progression from cachexy, etc. to multiple organ failure.

Cette invention se rapporte à des médicaments préventifs et/ou à des remèdes destinés à la défaillance de multiples organes et contenant en tant que principe actif le facteur-II cytotoxique tumoral (TCF-II) ou le facteur de croissance des hépatocytes (HGF). Ces médicaments s'avèrent utiles s'agissant de prévenir ou de traiter la dégradation de l'état général à la suite de brûlures, de coagulation intravasculaire disséminée (CIVD), de défaillance circulatoire, de choc hémorragique, de maladies infectieuses, de pancréatite aiguë, de troubles ischémiques, de syndrome hépatorénal, d'hémorragie du tractus digestif, d'une défaillance métabolique nutritionnel, ou la dégradation d'un patient atteint de cancer en phase terminale, du syndrome d'immuno-déficience acquise (SIDA), de radiolésions, etc. ainsi que la progression à partir de la cachexie, etc. vers la défaillance de multiples organes.

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