An aminoisoquinoline thrombin inhibitor with improved...

Details An aminoisoquinoline thrombin inhibitor with improved... An aminoisoquinoline thrombin inhibitor with improved...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/435 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2659154

The invention relates to the compound N-(2-oxo-2-propoxyethyl)-ß-phenyl-D-phenyl- alanyl-N-[(1-amino-6-isoquinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition comprising said compound, as well as to the use of the compound for the manufacture of a medicament for treating or for preventing thrombin mediated diseases.

La présente invention concerne le composé N-(2-oxo-2-propoxyéthyl)-ß-phényl-D-phényl-alanyl-N-[(1-amino-6-isoquinolinyl)méthyl]-L-prolinamide ou un sel pharmaceutiquement acceptable dudit composé, une composition pharmaceutique contenant ledit composé, aussi bien que l'utilisation du composé pour la fabrication d'un médicament permettant de traiter ou de prévenir des maladies médiées par la thrombine.

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