C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01)
Patent
CA 2682320
The present invention discloses a non-human animal model for a hereditary autosomal dominant disease. The non-human animal model expresses at least one phenotype associated with the disease and is obtained by a genetic determinant. The invention also relates to sperm cells and embryos comprising the genetic determinant for an autosomal dominant disease. Furthermore, methods for producing the non-human animal model, sperm cell, and embryos are disclosed.
La présente invention concerne un modèle animal non humain pour une maladie dominante autosomique héréditaire. Le modèle animal non humain exprime au moins un phénotype associé à la maladie et est obtenu par un déterminant génétique. L'invention concerne également des spermatocytes et des embryons comprenant le déterminant génétique pour une maladie dominante autosomique. En outre, l'invention concerne des procédés de production du modèle animal non humain, des spermatocytes et des embryons.
Bendixen Christian
Jakobsen Juhl Connie
Larsen Knud
Madsen Lone Bruhn
Thomsen Bo
Aarhus Universitet
Deeth Williams Wall Llp
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