C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 1/16 (2006.01) A61P 1/18 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01) A61P 11/00 (2006.01) A61P 13/12 (2006.01) A61P 19/04 (2006.01) A61P 19/10 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07K 16/46 (2006.01) G01N 33/53 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2635849
It is intended to provide an antibody against periostin having an anti-cell adhesion activity, particularly the anti-periostin antibody having an ability to neutralize an anti-cell adhesion action, and a preventive or therapeutic agent for a periostin-related disease using the antibody. It is also intended to provide detection and determination methods for the periostin in a sample using the antibody and a diagnostic method for a periostin-related disease by determining the amount of the periostin by the method.
L'invention concerne un anticorps dirigé contre la périostine qui présente une activité inhibitrice de l'adhésion cellulaire, en particulier l'anticorps anti-périostine capable de neutraliser une action inhibitrice de l'adhésion cellulaire, ainsi qu'un agent prophylactique ou thérapeutique pour prévenir ou traiter une maladie liée à la périostine, cet agent contenant ledit anticorps. L'invention concerne également des procédés de détection et de détermination de la périostine dans un échantillon au moyen de l'anticorps, ainsi qu'un procédé de diagnostic pour une maladie liée à la périostine, ce procédé de diagnostic consistant à déterminer le taux de périostine par le procédé susmentionné.
Katsuragi Naruto
Morishita Ryuichi
Taniyama Yoshiaki
Asubio Pharma Co. Ltd.
Daiichi Sankyo Company Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Osaka University
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