An antibody which recognizes phosphorylated polypeptides

Details An antibody which recognizes phosphorylated polypeptides An antibody which recognizes phosphorylated polypeptides

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) C12N 5/18 (2006.01) C12P 21/08 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2595164

The present invention relates to an antibody which recognizes an epitope consisting of Ser-Ile-A1-A2-A3-A4-Ser(PO3H2)-Pro-Gln-Leu-Ala-Thr-Leu-Ala-A5, and does not bind to an epitope consisting of Ser-Ile-A1-A2-A3-A4-Ser-Pro-Gln-Leu-Ala-Thr- Leu- Ala-A5, wherein A1 is Asp or Asn, A2 is Met or Leu, A3 is Val or Leu, A4 is Asp or Glu and A5 is Asp or Glu, a hybridoma producing the antibody, a kit comprising the antibody, and a method for diagnosis of a neurological disorder.

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