An antigenic epitope of the a determinant of hepatitis b...

Details An antigenic epitope of the a determinant of hepatitis b... An antigenic epitope of the a determinant of hepatitis b...

C - Chemistry, Metallurgy

07

K

C07K 14/02 (2006.01) A61K 39/29 (2006.01) C07K 7/08 (2006.01) C07K 16/08 (2006.01) G01N 33/576 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2251904

The subject invention relates to a peptide sequence corresponding to amino acid residues (117 to 128) of hepatitis B surface antigen and uses thereof. In particular, the peptide is an antigenic epitope and may therefore be used, for example, as a diagnostic reagent or in the production of a vaccine. Furthermore, the present invention also relates to a C(K/R)TC motif present within the peptide as well as to other peptides containing this motif.

La présente invention se rapporte à une séquence peptidique correspondant aux restes d'acides aminés 117 à 128 de l'antigène de surface de l'hépatite B et à ses utilisations. Le peptide est notamment un épitope antigénique et peut par conséquent être utilisé, par exemple, comme réactif de diagnostic ou dans la production d'un vaccin. La présente invention se rapporte également à un motif C(K/R)TC présent dans le peptide, ainsi qu'à d'autres peptides contenant ce motif.

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