An antimycobacterial pharmaceutical composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/131 (2006.01) A61K 31/4409 (2006.01) A61K 31/496 (2006.01) A61K 31/4965 (2006.01) A61P 31/06 (2006.01)

Patent

CA 2566440

An antimycobacterial combination and composition for treating tuberculosis are described. The compounds used are N-(3-[[4-(3- trifluoromethylphenyl)piperazinyl]methyl]-2-methyl-5-phenyl-pyrrolyl)-4- pyridylcarboxamide of formula (I) or a pharmaceutically acceptable non-toxic salt thereof and an amount of one or more first line antitubercular drugs.

La présente invention concerne d'une combinaison d'une composition antimycobactérienne destinée à traiter la tuberculose. Les composés utilisés sont N-(3-[[4-(3-trifluorométhylphényl)piperazinyl]méthyl]-2-méthyl-5-phényl-pyrrolyl)-4-pyridylcarboxamide représentés par la formule (I) ou un sel non toxique répondant aux normes pharmaceutiques de ces composés et une quantité d'un ou de plusieurs médicaments antituberculeux de première lignée.

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