A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4709 (2006.01) A61K 9/08 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01) A61K 47/40 (2006.01) A61P 1/04 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2443466
An aqueous preparation for injections which contains cilostazol or a pharmacologically acceptable salt thereof as the active ingredient and further contains a cyclodextrin. Due to the cyclodextrin, the solubility of the cilostazol or salt in the water is heightened. As a result, the aqueous preparation in the solution state has improved long-term stability.
Cette invention se rapporte à une préparation aqueuse pour injections, qui contient comme principe actif du cilostazol ou un sel de celui-ci acceptable sur le plan pharmacologique et qui contient en outre une cyclodextrine. Grâce à la présence de la cyclodextrine, la solubilité dans l'eau du cilostazol ou du sel est accrue. Il en résulte que la préparation aqueuse à l'état de solution possède une plus grande stabilité à long terme.
Inoue Fujio
Kawakami Keiichi
Nagayasu Shinya
Okamoto Hideshi
Fetherstonhaugh & Co.
Otsuka Pharmaceutical Co. Ltd.
Otsuka Pharmaceutical Factory Inc.
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