A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01) A61K 35/32 (2006.01) A61L 27/12 (2006.01) C04B 35/447 (2006.01) C04B 38/00 (2006.01) C12Q 1/02 (2006.01) C23C 30/00 (2006.01) A61F 2/00 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2230057
This invention relates to a bioactive artificial sintered composition for providing a morphology capable of consistently supporting bone cell activity thereon. The composition comprises stabilized calcium phosphate phases developed by the conversion of a hydroxyapatite substance in the presence of stabilizing entities at sintering temperatures into insolubilized and stabilized tricalcium phosphate. The present invention has numerous applications in medical diagnostics for the assessment of abnormal bone cell activity as well as for medical therapeutics, including bone and dental tissue replacement and repair as well as for ex vivo bone graft tissue engineering.
L'invention concerne une composition artificielle frittée qui est bioactive et qui a une morphologie lui permettant de servir de support de croissance fiable pour des cellules osseuses. La composition comprend des phases de phosphate de calcium stabilisées, obtenues par la conversion d'une substance du type hydroxyapatite en présence d'éléments stabilisants, à des températures de frittage, pour obtenir du phosphate tricalcique insoluble et stable. L'invention a de nombreuses applications dans le domaine des diagnostics médicaux pour mettre en évidence une activité anormale des cellules osseuses et dans le domaine chirurgical, en particulier pour la réfection et le remplacement de tissu osseux ou dentaire, ainsi que pour réaliser ex vivo des greffons de tissu osseux.
Langstaff Sarah Dorthea
Pugh Sydney M.
Sayer Michael
Smith Timothy J. N.
Millenium Biologix Inc.
Sim & Mcburney
Warsaw Orthopedic Inc.
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