C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/10 (2006.01) C07D 263/06 (2006.01) C07D 401/02 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 498/04 (2006.01) C07F 7/18 (2006.01)
Patent
CA 2262837
This invention relates to a key intermediate in the synthesis of an endothelin antagonist and the synthesis of this key intermediate using an asymmetric conjugate addition reaction.
L'invention concerne un intermédiaire clé dans la synthèse d'un antagoniste d'endothéline et dans la synthèse de cet intermédiaire clé au moyen d'une réaction d'addition par conjugué asymétrique.
Dolling Ulf H.
Frey Lisa F.
Tillyer Richard D.
Tschaen David M.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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