C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2440960
This invention relates to compositions and methods of detecting encophalopathies in a subject. This invention also relates to genetic markers, nucleic acid preparations or libraries, and kits for use in the implementation of said detection methods. The compositions and methods of this invention can also be used for the diagnosis, characterization, progression monitoring, etc. of encophalopathies, including at carly stages thereof, particularly Transmissible Spongiform Encephalopathies (TSE), including Bovine Spongiform Encephalopathies (BSE, "Mad Cow Disease").
L'invention concerne des compositions et des procédés de détection d'encéphalopathies chez un individu. L'invention concerne également des marqueurs génétiques, des préparations ou des bibliothèques d'acides nucléiques, ainsi que des ensembles destinés à être mis en oeuvre dans les procédés de détection selon l'invention. Les compositions et procédés selon l'invention peuvent également servir au diagnostic, à la caractérisation, au contrôle de progression etc. d'encéphalopathies, notamment à des stades précoces, en particulier d'encéphalopathies spongiformes transmissibles (EST) telles que l'encéphalopathie spongiforme bovine (ESB, <= maladiede la vache folle >=).
Fuentes Nathalie
Resink Annelies
Schweighoffer Fabien
Exonhit Therapeutics S.a.
Robic
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