C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/54 (2006.01) C07C 213/02 (2006.01) C07D 333/20 (2006.01)
Patent
CA 2511683
Provided is an efficient method for the preparation of 3-aryloxy-3-arylpropylamines, their optical stereoisomers, and pharmaceutically acceptable salts thereof. The process allows for the isolation of 3-aryloxy-3- arylpropylamines in high yield and purity. The present invention further relates to a process for producing fluoxetine, tomoxetine, norfluoxetine, duloxetine, nisoxetine, and their optically enriched (R)- and (S)-enantiomers.
Guntoori Bhaskar Reddy
Raheem Mohammed Abdul
Wang Zhi-Xian
Weeratunga Gamini
Apotex Pharmachem Inc.
Mckinnon Graham J.k.
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