An efficient method for preparing...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 217/54 (2006.01) C07C 213/02 (2006.01) C07D 333/20 (2006.01)

Patent

CA 2511683

Provided is an efficient method for the preparation of 3-aryloxy-3-arylpropylamines, their optical stereoisomers, and pharmaceutically acceptable salts thereof. The process allows for the isolation of 3-aryloxy-3- arylpropylamines in high yield and purity. The present invention further relates to a process for producing fluoxetine, tomoxetine, norfluoxetine, duloxetine, nisoxetine, and their optically enriched (R)- and (S)-enantiomers.

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