An enzymatic process for making morphine-6-glucuronide or...

Details An enzymatic process for making morphine-6-glucuronide or... An enzymatic process for making morphine-6-glucuronide or...

C - Chemistry, Metallurgy

12

P

C12P 19/60 (2006.01) C12N 11/08 (2006.01)

Patent

CA 2178082

A method of making morphine-6-glucuronide comprising the selective enzymatic cleavage of the 3-glucuronide moiety in morphine- 3,6-glucuronide or substituted morphine-6-glucuronide using at least one .beta.-glucuronide.

L'invention se rapporte à un procédé de fabrication de morphine-6-glucuronide consistant à effectuer le clivage enzymatique sélectif de la fraction 3-glucuronide dans le morphine-3,6-glucuronide ou le morphine-6-glucuronide substitué à l'aide d'au moins un .beta.-glucuronide.

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