C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/40 (2006.01) A61K 51/04 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12P 7/54 (2006.01)
Patent
CA 2459514
There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has the capacity to catalyse the synthesis of a fluoronucleoside compound. (Formula I).
L'invention concerne un procédé de synthèse de fluoronucléoside, ce procédé consistant à mélanger un substrat et une enzyme, provenant de <i>Streptomyces cattelya</i>, en tant que catalyseur. Il est possible d'utiliser le procédé afin de produire un fluoronucléoside marqué au ?18¿F. L'invention concerne aussi une enzyme provenant de <i>Streptomyces cattelya</i> qui possède la capacité de catalyser la synthèse d'un fluoronucléoside.
O'hagan David
Schaffrath Christoph
Norton Rose Canada S.e.n.c.r.l.,s.r.l./llp
The University Court Of The University Of St Andrews
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