C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/08 (2006.01) A61K 47/48 (2006.01) A61P 7/06 (2006.01) C07K 14/505 (2006.01)
Patent
CA 2708819
What is provided is an EPO mimetic peptide derivatives defined as formula (I) and its pharmaceutical salt, the preparation thereof, wherein R1, R2, R3, R4, R5, n1, n2 are defined as described in description. A composition comprising of an EPO mimetic peptide derivatives defined as formula (I) and its pharmaceutical salt. The uses of the derivatives and its pharmaceutical salt, as well as the uses of the composition described above in treatment of diseases characterized by a deficiency of EPO or a low or defective red blood cell population. R1-R2-(CH2)n1-R3-(CH2)n2-R4-R5 (I)
L'invention concerne un dérivé de peptide mimétique d'érythropoïétine défini par la formule (I) et son sel pharmaceutique, ainsi que sa préparation. Dans ladite formule, R1, R2, R3, R4, R5, n1 et n2 sont définis tels que dans la description. L'invention concerne également une composition comprenant un peptide mimétique d'érythropoïétine défini par la formule (I) et son sel pharmaceutique. L'invention concerne également les utilisations du dérivé et de son sel pharmaceutique, ainsi que les utilisations de ladite composition dans le traitement de maladies caractérisées par une déficience de l'érythropoïétine ou une population faible ou déficiente d'érythrocytes. R1- R2-(CH2)n1-R3-(CH2)n2-R4-R5 (I)
Jiang Tao
Lu Aifeng
Sun Changan
Wang Yali
Wu Wentao
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Jiangsu Hansoh Pharmaceutical Co. Ltd.
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