An expression vector and a method thereof

Details An expression vector and a method thereof An expression vector and a method thereof

C - Chemistry, Metallurgy

12

N

C12N 15/67 (2006.01) C07K 14/715 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2736580

The present invention relates to vectors and compounds for the expression of recombinant soluble proteins. More particularly, the present invention relates to nucleic acid molecules, expression vectors, and host cells for the expression of recombinant soluble Tumour Necrosis Factor Alfa receptor (TNFR) - Human IgG Fc fusion protein. The invention further relates to methods for preparing recombinant soluble Tumour Necrosis Factor Alfa receptor (TNFR) - Human IgG Fc fusion protein using the host cells transfected with the expression vectors.

La présente invention concerne des vecteurs et des composés pour l'expression de protéines solubles recombinantes. Plus particulièrement, la présente invention concerne des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes pour l'expression de la protéine de fusion récepteur du facteur de nécrose tumorale alfa (TNFR) Fc de IgG humaine, soluble, recombinante. L'invention concerne en outre des procédés de préparation de la protéine de fusion récepteur du facteur de nécrose tumorale alfa (TNFR) Fc de IgG humaine, soluble, recombinante, à l'aide des cellules hôtes transfectées par les vecteurs d'expression.

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