An extractive of piper laetisipicum c.dc., its process and...

A - Human Necessities – 61 – K

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A61K 36/67 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2589013

An extractive of Piper laetispicum C.DC., its process and its uses for preparing a medicine, health care product and food additive for treating and preventing diseases correlated with monoamine transmitter ,such as 5-HTA noradrenalin dopamine and so on. The extractive is processed through impregnating or percolating at common temperature or <=70~C or using supercritical fluid extraction method, to obtain higher alkaloid content and higher biological activity, compared to using reflux method of prior art.

La présente invention a pour objet un extrait de Piper laetispicum C.DC., son procédé d~élaboration et son application dans la préparation d~un médicament, d~un produit sanitaire ou d~un additif alimentaire destiné au traitement prophylactique et thérapeutique des maladies liées aux transmetteurs de type monoamine, tels que le 5-HTA, la noradrénaline, la dopamine, etc. L~extrait est obtenu par imprégnation ou percolation à température ambiante ou <=70 °C, ou en employant une méthode d~extraction par fluide supercritique, afin d'aboutir à une teneur en alcaloïdes plus élevée, ainsi qu'à une activité biologique plus importante, ce qui représente une amélioration par rapport à la méthode au reflux décrite dans l'art antérieur.

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