An image guide and method for sub-micron imaging and...

G - Physics – 01 – N

Patent

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G01N 21/64 (2006.01) G01N 21/77 (2006.01)

Patent

CA 2358558

The present invention is an image guide which has applications in such areas as endoscopy and industrial imaging. This invention utilizes gradient-index optical fiber in order to produce an image guide with improved performance characteristics. These improved performance characteristics include increased brightness, enhancedresolution, greater flexibility, and smaller diameter. The subject invention also pertains to a method and instrumentation for in vivo micro- imaging of structure and function at the subcellular level. Different immobilization methods for the preparation of a variety of biosensor probes can be utilized for attachment to the subject probes.

L'invention concerne un guide-image utilisé dans des applications telles que l'endoscopie et l'imagerie industrielle. Grâce à ses fibres optiques à gradient d'indice, le dispositif offre de meilleures caractéristiques en performance, à savoir par exemple amélioration de la luminosité, de la résolution et de la flexibilité, et réduction du diamètre. L'invention concerne également un procédé et des instruments permettant de former in vivo des micro-images de structure ou de fonction au niveau sous-cellulaire. Différents procédés d'immobilisation permettent de préparer une variété de sondes de biocapteurs utilisés pour la fixation desdites sondes.

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