An immune disease remedy, treatment method and preventive...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/24 (2006.01) A61K 35/14 (2006.01) A61K 38/20 (2006.01) C07K 14/54 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2265505

The present invention discloses a remedy, preventive agent, treatment method and preventive method for immune diseases of dogs and cats. As an active ingredient of the remedy and preventive agent, canine interleukin 12 is used. Specifically, the present invention relates to an immune disease remedy and preventive agent: of dogs and cats comprising canine interleukin 12 of a heterodimer formed by an amino acid sequence identical with or having a part of Sequence number:1 or Sequence number:11 and an amino acid sequence identical with or having a part of Sequence number:2 or Sequence number:12. Furthermore, the present invention relates to an immune disease treating method and preventive method for dogs and cats which is characterized in injecting the immune disease remedy and preventive agent of dogs and cats into a dog or cat.

Cette invention concerne des agents thérapeutique et prophylactique destinés au traitement de maladies immunologiques chez les chiens et les chats, lesquels agents contiennent un ingrédient actif qui comprend une interleukine 12 canine obtenue par génie génétique. D'une manière plus précise, les agents thérapeutique et prophylactique contiennent une interleukine 12 canine comprenant une séquence d'acide aminé qui est identique à une partie ou à la totalité des séquences N DEG ID SEQ: 1 ou N DEG ID SEQ: 11, ainsi qu'une séquence d'acide aminé qui est identique à une partie ou à la totalité des séquences N DEG ID SEQ: 2 ou N DEG ID SEQ: 12. Ces séquences d'acide aminé sont obtenues en formant un dimère hétéro. Cette invention concerne également des procédés de traitement et de prévention de maladies immunologiques chez les chiens et les chats, lesquels procédés consistent à injecter à un chien ou à un chat l'agent prophylactique ou thérapeutique susmentionnés.

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