C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/29 (2006.01) A61K 38/00 (2006.01) C07K 16/12 (2006.01) C12N 15/31 (2006.01)
Patent
CA 2555413
The present invention is directed to the cloning, sequencing, expression, and characterization of an immunoreactive ferric. binding protein (Fbp) (38-kDa) protein of Ehrlichia canis encoded by a polynucleotide therefor. In particular embodiments, the protein is employed in an immunogenic composition, such as a vaccine. Methods to induce an immune reaction in an individual with compositions of the invention are provided.
La présente invention a trait au clonage, au séquençage, à l'expression et à la caractérisation d'une protéine (38-kDa) de protéine de liaison ferrique de Ehrlichia canis codée par un polynucléotide. Dans des modes de réalisation particuliers, la protéine est utilisée dans une composition immunogène, telle qu'un vaccin. L'invention a également trait à des procédés d'induction d'une réaction immunitaire chez un individu avec les compositions de l'invention.
Doyle Christopher Kuyler
Mcbride Jere W.
Walker David H.
Goudreau Gage Dubuc
Research Development Foundation
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