An immunostimulant and antineoplastic glycan obtained from...

Details An immunostimulant and antineoplastic glycan obtained from... An immunostimulant and antineoplastic glycan obtained from...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/04 (2006.01) A61K 45/05 (1995.01)

Patent

CA 2232501

The present invention is a glycan compound with antineoplastic and immunostimulant properties for treating human cancers and as an adjuvant in the formulation of a tuberculosis vaccine, said compound containing at least one component from the class of sugars including arabinose, mannose, glucose and galactose, together with a peptide side chain, having an approximate 60-65 kDa molecular weight, and being readily water-soluble and heat-stable. The invention also is comprised of a process for extracting the glycan compound from the Mycobacterium vaccae, a non-pathogenic, rapid growing member of the mycobacteria.

La présente invention concerne un glycanne ayant des propriétés antinéoplasiques et immunostimulantes, pour traiter les cancers humains et comme adjuvant pour la formulation d'un vaccin anti-tuberculeux. Ce composé contient au moins un composant de la classe des sucres, dont l'arabinose, le mannose, le glucose et le galactose, ainsi qu'une chaîne latérale peptidique, ayant une poids moléculaire correspondant à environ 60-65 kDa. Ce composé se dissout facilement dans l'eau et est stable à la chaleur. L'invention concerne également un procédé pour extraire le glycanne de Mycobacterium vaccae, une mycobactérie non pathogène à croissance rapide.

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