An improved laundry detergent composition comprising amylase

C - Chemistry – Metallurgy – 11 – D

Patent

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Details

C11D 3/386 (2006.01) C12N 9/28 (2006.01)

Patent

CA 2216316

Laundry detergents comprising novel alpha-amylase mutants derived from the DNA sequences of naturally occuring or recombinant alpha-amylases are disclosed. The mutant alpha-amylases, in general, are obtained by in vitro modifications of a precursor DNA sequence encoding the naturally occuring or recombinant alpha-amylase to generate the substitution (replacement) or deletion of one or more oxidizable amino acid residues in the amino acid sequence of a precursor alpha-amylase. Such laundry detergents containing mutant alpha-amylases have increased cleaning ability stability and/or altered pH performance profiles and/or altered thermal stability as compared to the precursor.

Cette invention concerne des détergents de lessive contenant de nouveaux mutants d'alpha-amylase dérivés des séquences d'ADN d'alpha-amylases recombinantes ou d'origine naturelle. Les alpha-amylases mutantes sont obtenues de manière générale par des modifications in vitro d'une séquence d'ADN précurseur codant pour les alpha-amylases recombinantes ou d'origine naturelle, ceci afin d'engendrer la substitution (le remplacement) ou l'effacement d'un ou de plusieurs résidus d'acides aminés oxydables dans la séquence d'acides aminés d'une alpha-amylase précurseur. Ces détergents de lessive contenant des alpha-amylases mutantes possèdent une plus grande stabilité pour ce qui est de leur capacité de nettoyage et/ou des caractéristiques de performance pH modifiées et/ou une stabilité thermique modifiée en comparaison du précurseur.

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