An improved pharmaceutical composition for treating male...

A - Human Necessities – 61 – K

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A61K 9/08 (2006.01) A61K 9/00 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2391968

The invention disclosed in this application relates to a novel pharmaceutical composition containing sildenafil useful for nasal administration for the treatment of male erectile dysfunction due to organic, psychogenic and mixed causes. The composition is also effective in patients with erectile dysfunction due to spinal cord injury. The pharmaceutical composition of the present invention is in the form of a solution or a colloidal dispersion in a pharmaceutical vehicle filled into specially designed dosing device for nasal administration. The invention disclosed in this application also provides a method for preparing the pharmaceutical composition containing sildenafil for nasal application for the treatment of male erectile dysfunction.

La présente invention concerne une nouvelle composition pharmaceutique à base de sildénafil administrée par voie nasale pour traiter la dysérection masculine d'origines diverses, et notamment organique et psychogène. Cette composition est également efficace chez les patients souffrant de dysérection due à une lésion de la moelle épinière. par ailleurs, cette composition pharmaceutique se présente sous forme de solution ou de dispersion colloïdale contenue dans un excipient pharmaceutique et logée dans un doseur spécialement conçu pour l'administration par voie nasale. En outre, cette invention concerne un procédé de préparation d'une composition pharmaceutique à base de sildénafil devant être administrée par voie nasale en vue de traiter la dysérection masculine.

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