An improved process for preparation of bicalutamide

Details An improved process for preparation of bicalutamide An improved process for preparation of bicalutamide

C - Chemistry, Metallurgy

07

C

C07C 315/02 (2006.01) C07C 317/46 (2006.01)

Patent

CA 2635461

A process for preparation of Bicalutamide of formula (I), comprising oxidation of compound of formula (II), with potassium permanganate in presence of water or a mixture of water and water miscible solvent and isolating Bicalutamide of formula (I) thereof.

L~invention concerne un procédé de fabrication de bicalutamide de formule (I) comprenant l'oxydation d'un composé de formule (II) avec du permanganate de potassium en présence d'eau ou d'un mélange d'eau et d'un solvant miscible avec l'eau et l'isolation du bicalutamide de formule (I).

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