An improved process for the conversion of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 285/125 (2006.01)

Patent

CA 2280668

The present invention provides a process for making thiadiazole sulfones. In particular, the present process is used to make 2--(methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole using catalytic oxidation in the presence of a suitable oxidizing agent. The catalyst system used for the oxidation reaction is a mixture of glacial acetic acid and a tungsten catalyst. The tungsten catalyst is preferably selected from the group consisting of sodium tungstate, potassium tunstate, and tungstic acid.

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