An improved process for the preparation of amino methyl...

Details An improved process for the preparation of amino methyl... An improved process for the preparation of amino methyl...

C - Chemistry, Metallurgy

07

C

C07C 227/42 (2006.01) C07C 229/28 (2006.01)

Patent

CA 2506563

This invention relates to an improved process for the preparation of amino methyl cyclo alkane acetic acids. This invention particularly relates to an improved process for the preparation of gabapentin (which is chemically known as 1-aminomethyl-1-cyclohexaneacetic acid): (see formula I) which is a very well known agent useful for the treatment of epilepsy and other cerebral disorders. In the chemical series of 1-amino methyl cyclo alkane-1-acetic acids, Gabapentin has been developed as a drug having anti convulsive properties.

L'invention concerne un procédé amélioré de préparation d'acides amino-méthyl-cycloalcane-acétiques. Elle porte notamment sur un procédé amélioré de préparation de gabapentine (chimiquement connu sous le nom d'acide 1-aminométhyl-1-cyclohexaneacétique) qui est un agent très connu, utile pour le traitement de l'épilepsie et d'autres troubles cérébraux. Dans la série chimique d'acides 1-aminométhyl-cycloalcane-1-acétiques, le Gabapentine, qui est un acide 1-aminométhyl-cyclohexane-1-acétique a été mis au point sous forme de médicament possédant des propriétés anticonvulsives.

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