C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) A61K 49/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2219976
A transgenic mouse capable of expressing human elastin promoter ois provided. Mouse fibroblast cultures derived from this transgenic mouse are also provided. In addition methods of identifiying compounds capable of inhibiting cutaneous photodamaged with this transgenic mouse or fibroblast cultures derived from these mice are provided.
L'invention décrit une souris transgénique capable d'exprimer le promoteur de l'élastine humaine, ainsi que des cultures de fibroblastes de souris tirées de ladite souris transgénique. Elle décrit également des procédés permettant d'identifier des composés capables d'inhiber les lésions cutanées provoquées par les rayonnements solaires à l'aide de ladite souris ou des cultures de fibroblastes tirées de souris transgéniques.
Bernstein Eric
Uitto Jouni
Bernstein Eric F.
Borden Ladner Gervais Llp
Thomas Jefferson University
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