An inhalable medicament

Details An inhalable medicament An inhalable medicament

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 9/19 (2006.01) A61K 31/46 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2692606

This invention relates to an inhalable medicament and in particular to a solid- state form of tiotropium bromide, namely solid amorphous particles comprising an intimate admixture of tiotropium bromide together with a pharmaceutically accept-able co-solid having a glass transition temperature of at least - 50°C, such as a sugar and/or a sugar derivative.

Cette invention porte sur un médicament inhalable et, en particulier, sur une nouvelle forme à état solide de bromure de tiotropium, à savoir des particules amorphes solides comprenant un mélange intime de bromure de tiotropium et d'un Co-solide pharmaceutiquement acceptable ayant une température de transition vitreuse d'au moins -50 °C, tel qu'un sucre et/ou un dérivé de sucre.

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