An insulin improving agent containing adiponectin

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/22 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2474964

It is intended to provide insulin resistance improving agents which contain, as the active ingredient, the C-terminal side spherical region of adiponectin C, adiponectin or genes thereof. It is also intended to provide remedies for type 2 diabetes which contain, as the active ingredient, the C-terminal side spherical region of adiponectin C, adiponectin or genes thereof. Thus, insulin resistance, which is induced by fat-rich diet and accompanied by obesity, can be improved and type 2 diabetes amounting the major part of diabetes can be treated.

L'invention concerne des agents améliorant la résistance à l'insuline, qui contiennent, comme principe actif, la région sphérique latérale C-terminale de l'adiponectine C, de l'adiponectine ou de leurs gènes. L'invention concerne en outre des remèdes contre le diabète non insulino-dépendant, qui contiennent, comme principe actif, la région sphérique latérale C-terminale de l'adiponectine C, de l'adiponectine ou de leurs gènes. La résistance à l'insuline, qui est induite par un régime riche en graisse et s'accompagne de l'obésité, peut être améliorée; et le diabète non insulino-dépendant, type de diabète le plus répandu, peut être traité.

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