An integrin heterodimer and an alpha subunit thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/04 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2375876

A recombinant or isolated integrin heterodimer comprising a novel subunit .alpha.11 in association with a subunit .beta. is described. The integrin or the subunit .alpha.11 can be used as marker or target of all types of cells. The integrin or subunit .alpha.11 thereof can be used as marker or target in different physiological or therapeutic methods. They can also be used as active ingredients in pharmaceutical compositions and vaccines.

Cette invention concerne un hétérodimère d'intégrine recombinant ou isolé comprenant une nouvelle sous-unité .alpha.11 en association avec une sous-unité .beta.. L'intégrine ou la sous-unité .alpha.11 conviennent comme marqueur ou cible pour tous types de cellules, notamment dans le cadre de diverses méthodes physiologiques ou thérapeutiques. Elles peuvent également être utilisées comme ingrédients actifs dans des compositions pharmaceutiques et des vaccins.

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