An optical resolution of 4-halogeno-3-alkanoyloxybutyronitrile

Details An optical resolution of 4-halogeno-3-alkanoyloxybutyronitrile An optical resolution of 4-halogeno-3-alkanoyloxybutyronitrile

C - Chemistry, Metallurgy

12

P

C12P 13/00 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2303697

A process for preparation of optically active 4-halogeno-3-hydoxybutyronitrile and 4-halogeno-3- alkanoyloxybutyronitrile, which are simply and economically prepared by reacting a racemic 4-halogeno-3- alkanoyloxybutyronitrile with a microorganism such as a strain of the genus Pseudomonas or the genus Enterobacter, which has the activity stereoselectively hydrolyzing the ester portion, its culture broth or an enzymes) derived from the microorganism or an enzyme preparation such as a lipase preparation.

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