An optically active pyridine derivative and a medicament...

Details An optically active pyridine derivative and a medicament... An optically active pyridine derivative and a medicament...

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/5365 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2478942

An optically active (-)-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-[(3S)-3- piperidinyl]-1,4-dihydro-2H-pyrido [2,3-d][1,3]oxazin-2-one of the formula (I) or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.

L'invention concerne une (-)-7-[2-(cyclopropylméthoxy)-6-hydroxyphényl]-5-[(3<I>S</I>)-3-pipéridinyl]-1,4-dihydro-2<I>H</I>-pyrido [2,3-d][1,3]oxazin-2-one optiquement active de formule (I) ou un sel dudit composé. Ce composé présente une excellente activité anti-inflammatoire et une autre activité biologique.

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