Anaerobic bacterium as a drug for cancer gene therapy

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/20 (2006.01) A61K 35/74 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/195 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2342040

The present invention provides a bacterium belonging to the genus Bifidobacterium, by which DNA coding for a protein having an antitumor activity or DNA coding for a protein having the activity of converting a precursor of an antitumor substance into the antitumor substance is delivered to tumor tissues specifically under anaerobic conditions thereby expressing the protein encoded by the DNA, as well as a pharmaceutical composition comprising said anaerobic bacterium.

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