Analgesic compositions

A - Human Necessities – 61 – K

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167/227

A61K 31/47 (2006.01) A61K 31/485 (2006.01)

Patent

CA 1234353

Abstract An analgesic composition in parenteral or sublingual dosage form comprising an active dose of buprenorphine and an amount of naloxone sufficient to prove aversive to a narcotic addict by parenteral administration but insufficient to compromise the analgesic action of the buprenorphine. Preferably the parenteral dosage form contains naloxone and buprenorphine within the weight ratio of 1:3 to 1:1 and the sublingual form within the ratio 1:2 to 2:1.

469361

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