Analgesic compounds

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/08 (2006.01)

Patent

CA 2685720

The invention refers to novel compounds (e.g., peptides) that are useful in the treatment of pain. The compounds are useful in treating both chronic and acute pain. The peptides can act as analgesics and/or anti-nociceptive agents. According to an embodiment, the invention refers to an isolated peptide that comprises an amino acid sequence that is at least 70% identical to the 14 amino acid sequence: pGlu-Phe-Ser-Pro-Glu-Asn-Ala-Gln-Gly-Glu-Ser-Gln-Pro-Ala (SEQ ID NO:2).

La présente invention concerne de nouveaux composés (par exemple, des peptides) qui sont utiles dans le traitement de la douleur, qu'elle soit chronique qu'aiguë. Les peptides peuvent agir comme des analgésiques et/ou des agents antinociceptifs. Selon un mode de réalisation, l'invention se rapporte à un peptide isolé comportant une séquence d'acides aminés qui est au moins identique à 70 % à la séquence de 14 acides aminés : pGlu-Phe-Ser-Pro-Glu-Asn-Ala-Gln-Gly-Glu-Ser-Gln-Pro-Ala (SEQ ID NO : 2).

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