Analgesic containing a pyrimidine derivative

A - Human Necessities – 61 – K

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167/219

A61K 31/505 (2006.01)

Patent

CA 1317549

Analgesic Abstract New analgesics contain compounds of the formula I Image wherein =A-8- is =CH-CH= or =N-CR2=, Alk is an alkylene group having 2-4 C atoms, R1 is H, dialkylaminoalkyl, carboxyalkyl, alkoxy- carbonylalkyl, carbamoylalkyl, N-alkylcarbamoyl- alkyl or N,N-dialkylcarbamoylalkyl, Y is CH or N, Z is a bond or -CO-, Ar is a phenyl, thienyl or pyridyl group which is unsubstituted or substituted one or more times by alkyl, alkoxy, F, Cl, Br, I and/or CF3, and R2 is H, alkyl, alkoxy or alkylthio, in which the alkyl, alkoxy and alkylthio groups each con- tain 1-4 C atoms, and/or one of its physiologically accep- table salts.

582914

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