Analgesic peptide and process for the preparation thereof

Details Analgesic peptide and process for the preparation thereof Analgesic peptide and process for the preparation thereof

C - Chemistry, Metallurgy

07

K

167/205, 530/7.0

C07K 7/08 (2006.01) C07K 14/665 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1248089

Abstract of the disclosure A novel peptide having the primary structure: N-Me-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D?Ile-Arg-Pro-Lys- D?Leu-Lys-Trp-NH2 (in which D?Ile and D?Leu represent a D-Ile and a D-Leu residue respectively, other abbreviations of amino acids represent each an L-amino acid residue and Me represents a methyl group), which exhibits a remarkable analgesic effect when administered peripherally. A process for the preparation thereof by a solid phase method is also disclosed.

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