Analogs of 4-hydroxyisoleucine and uses thereof

Details Analogs of 4-hydroxyisoleucine and uses thereof Analogs of 4-hydroxyisoleucine and uses thereof

C - Chemistry, Metallurgy

07

C

C07C 229/22 (2006.01) C07C 229/12 (2006.01) C07C 229/28 (2006.01) C07C 229/30 (2006.01) C07C 229/36 (2006.01) C07C 229/50 (2006.01) C07C 271/22 (2006.01) C07C 309/18 (2006.01) C07C 311/19 (2006.01) C07D 207/16 (2006.01) C07D 211/60 (2006.01) C07D 257/04 (2006.01) C07D 295/18 (2006.01) C07D 307/32 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2598365

The invention relates to analogs of 4-hydroxyisoleucine, and to lactones, pharmaceutically acceptable salts, and prodrugs thereof, to processes for their preparation, and to pharmaceutical compositions comprising the same. The analogs of the invention stimulate both glucose uptake and insulin secretion, and might thus be useful for the prevention and treatment of disorders of carbohydrate or lipid metabolism, including diabetes mellitus (type 1 and type 2 diabetes), pre-diabetes, and Metabolic Syndrome.

L'invention concerne des analogues de 4-hydroxyisoleucine, des lactones, des sels pharmaceutiquement acceptables et des promédicaments de ceux-ci, leurs procédés de préparation et des compositions pharmaceutiques utilisant lesdits analogues. Les analogues de l'invention stimulent à la fois l'absorption du glucose et la sécrétion d'insuline, et peuvent donc être utilisés pour prévenir et traiter des troubles du carbohydrate ou du métabolisme lipidique, notamment, le diabète sucré (diabète de types 1 et 2), le pré-diabète et le syndrome métabolique.

Affiliated with

Also associated with

Rating

Analogs of 4-hydroxyisoleucine and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Analogs of 4-hydroxyisoleucine and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Analogs of 4-hydroxyisoleucine and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1585389