Analogs of carbonic anhydrase inhibitors and their use as...

Details Analogs of carbonic anhydrase inhibitors and their use as... Analogs of carbonic anhydrase inhibitors and their use as...

C - Chemistry, Metallurgy

07

D

C07D 285/135 (2006.01) A61K 31/18 (2006.01) A61K 31/425 (2006.01) A61K 31/70 (2006.01) C07C 311/29 (2006.01) C07C 311/39 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2084658

2084658 9200287 PCTABS00010 Analogs are prepared of the carbonic anhydrase inhibitors methazolamide, and dichlorphenamide. The analogs link a cleavable functional group to the pharmacologically active carbonic anhydrase inhibitor resulting in compounds of improved corneal permeability, which are non-irritable to the eye and which are effective topically to inhibit intraocular pressure.

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