Analogs of oxetanyl purines and pyrimidines

Details Analogs of oxetanyl purines and pyrimidines Analogs of oxetanyl purines and pyrimidines

C - Chemistry, Metallurgy

07

D

167/211, 260/255

C07D 405/02 (2006.01) A61K 31/505 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 473/34 (2006.01) C07F 9/645 (2006.01)

Patent

CA 2032422

-119- ANALOGS OF OXETANYL PURINES AND PYRIMIDINES ABSTRACT OF THE DISCLOSURE A compound of the formula: Image wherein B is a purin-9-yl group or a heterocyclic isostere of a purin-9-yl group; or a pyrimidin-1-yl group or a heterocyclic isostere of a pyrimidin-1-yl group; A is -CH- or A-G taken together is -C(=O)-, -C(=CH2)-, -C(OH)(CH20H)- or Image and G and D are functional groups; or a pharmaceutically acceptable salt or ester thereof.

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