C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.08, 167/10
C07K 5/083 (2006.01) A61K 38/06 (2006.01) C07K 5/02 (2006.01) C07K 7/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2020129
CASE 3076 NEW ANALOGUES OF ALL-BOND RETROINVERTED THYMOPENTIN, THE METHOD FOR THE SYNTHESIS OF THE SAME AND THEIR EMPLOY- MENT FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS ABSTRACT New thymopentin (TP5) analogues whose bonds in the peptide chain are all retro-inverted are disclosed. Such new compounds have the following general for- mula (I) Image (I) wherein R is hydrogen or an acyl radical, and R1 is a group of the formula -OR2, wherein R2 is a hydrogen atom or a hydrocarbon radical, and the corresponding basic or acid addition salts which are pharmaceutically accept- able. The new compounds have immunostimulating activity.
Mariotti Sabina
Nencioni Luciano
Pessi Antonello
Sisto Alessandro
Villa Luigi
Robic
Sclavo S.p.a.
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