Analogues of bestatin

C - Chemistry – Metallurgy – 07 – C

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260/518, 260/526

C07C 101/02 (1980.01) C07C 101/447 (1980.01)

Patent

CA 1104157

ABSTRACT Bestatin, which is [(2S,3R)-3-amino-2- hydroxy-4-phenylbutanoyl]-L-leucine, and related com- pounds which inhibit aminopeptidase B, leucino amino- peptidase and Bleomycin hydrolase, enhance the anti- tumor effect of Bleomycin and exhibit an antifertility effect were synthesized and tested.

363896

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