Analogues of insulin-like growth factor-1

C - Chemistry – Metallurgy – 07 – K

Patent

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530/7.1, 167/103

C07K 14/65 (2006.01) A61K 38/30 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341207

A peptide analogue of mammalian insulin-like growth factor-1 wherein form 1 to 5 amino acid residues are absent form the N-terminal. Such peptide analogue is useful in the treatment of protein accumulation deficiencies or protein loss in mammals. Normally such deficiencies are associated with cancer, cystic fibrosis, Duchenne muscular dystrophy, Becker dystrophy, autosomal recessive dystrophy and polymyositis.

583939

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