Analysing volatile organic compounds

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/04 (2006.01) C12Q 1/22 (2006.01)

Patent

CA 2649668

The invention describes the use of a biomarker pentylfuran to detect bacterial and/or fungal pathogens. Pentylfuran is released from certain pathogens and detected in the headspace gas of an in vitro culture or in the breath sample of a patient. Pentylfuran is particularly useful in the detection of Aspergillusspecies, especially Aspergillus fumigatus which is a pathogen of humans.

La présente invention décrit l'emploi d'un biomarqueur de type pentylfurane pour la détection d'agents pathogènes bactériens et/ou fongiques. Le pentylfurane est libéré par certains agents pathogènes, puis détecté dans l'atmosphère d'une culture in vitro ou dans l'échantillon d'air expiré par un patient. Le pentylfurane est particulièrement employé dans la détection de l'espèce Aspergillus, plus particulièrement Aspergillus fumigatus qui est un agent pathogène pour l'homme.

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