Analysis and prediction of protein functional subtypes from...

Details Analysis and prediction of protein functional subtypes from... Analysis and prediction of protein functional subtypes from...

G - Physics

06

F

G06F 17/00 (2006.01) G06F 17/30 (2006.01) G06F 19/00 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2322751

Here we present a method for analysis and prediction of functional sub-types from multiple protein sequence alignments. Given an alignment and set of proteins grouped into sub-types according to some definition of function, such as enzymatic specificity, the method identifies positions that are indicative of functional differences by subtraction of sequence profiles, and analysis of positional entropy in the alignment.

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