Analysis chip and analysis method

G - Physics – 01 – N

Patent

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Details

G01N 33/53 (2006.01) C12M 1/00 (2006.01) C12N 15/09 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2671866

An analysis chip which has a baseboard having a selectively binding substance immobilized on the surface thereof, a covering member bonded to this baseboard and fine particles contained or injected in a movable state within a space that is formed between the baseboard and the covering member, wherein the surface of the fine particles is coated with a surfactant. Owing to this construction, it is possible to prevent the formation of bubbles inhibiting a selective reaction between a test substance and the selectively binding substance having been immobilized so that data variation and lowering in the sensitivity can be regulated and the reproducibility of the measurement can be elevated.

L'invention concerne une puce d'analyse qui présente une plaque de base avec une substance se liant de manière sélective immobilisée sur sa surface, un membre couvrant lié à cette plaque de base et des particules fines contenues ou injectées dans un état mobile au sein d'un espace qui est formé entre la plaque de base et le membre couvrant, la surface des particules fines étant revêtue d'un surfactant. Grâce à cette construction, il est possible d'empêcher la formation de bulles inhibant une réaction sélective entre une substance à tester et la substance se liant de manière sélective ayant été immobilisée de telle manière que la variation des données et l'abaissement de la sensibilité peuvent être régulés et la reproductibilité de la mesure peut être élevée.

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