Analysis of chemically crosslinked cellular samples

Details Analysis of chemically crosslinked cellular samples Analysis of chemically crosslinked cellular samples

G - Physics

01

N

G01N 1/30 (2006.01)

Patent

CA 2549751

A method of analyzing cellular crosslinked (aldehyde fixed) and embedded cellular samples by cleaving the crosslinks and retrieving the antigens in a heating or irradiation step. The analysis is typically based on mass spectroscopy.

L'invention concerne un procédé pour analyser des échantillons cellulaires réticulés (fixation aldéhyde) et cellulaires enchâssés, par clivage des liaisons de réticulation et extraction des antigènes lors d'une étape de chauffage ou d'irradiation. Cette analyse est généralement fondée sur une spectroscopie de masse.

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