Analysis of nucleic acids by digital pcr

Details Analysis of nucleic acids by digital pcr Analysis of nucleic acids by digital pcr

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2694619

The present invention provides a method for analyzing nucleic acids for their lengths and relative abundance in a sample, based on digital amplification of individual template molecules. This invention has many applications, including those in noninvasive prenatal diagnosis, transplantation monitoring, and the detection and monitoring of cancers and virus-associated dis-eases.

La présente invention porte sur un procédé pour analyser des acides nucléiques pour leurs longueurs et leur abondance relative dans un échantillon, sur la base d'une amplification numérique modèles de molécules individuelles. Cette invention possède de nombreuses applications, comprenant celles dans un diagnostic prénatal non invasif, une surveillance de transplantation, et la détection et la surveillance de cancers et de maladies associées à un virus.

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