Analytical device and method for using same

G - Physics – 01 – N

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150/3, 167/44

G01N 33/543 (2006.01) G01N 33/52 (2006.01) G01N 33/552 (2006.01) G01N 33/576 (2006.01)

Patent

CA 1274174

ABSTRACT OF THE DISCLOSURE An improved, solid phase analytical devise for determining the presence or amount of a substance in a test sample, as well as an assay method using the devices is disclosed. The device comprises a porous, non-bibulous fiber matrix impregnated with a hydrophobic polymer which forms a surface coating on at least a portion of the fibers of the matrix. The device also comprises a reagent capable of reaction with the substance in the sample; the polymer is capable of retaining the reagent within the matrix. The device of the invention is particularly advantageous for use in enzyme immunoassays.

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