Analytical element and method for determination of total...

C - Chemistry – Metallurgy – 12 – Q

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150/15.1, 150/3.

C12Q 1/26 (2006.01) C12Q 1/32 (2006.01) G01N 1/00 (2006.01) G01N 21/77 (2006.01)

Patent

CA 1279563

ANALYTICAL ELEMENT AND METHOD FOR DETERMINATION OF TOTAL LACTATE DEHYDROGENASE Abstract of the Disclosure A multilayer analytical element exhibits improved precision in the assay of total lactate dehydrogenase (LDH). The element also provides reduced susceptibility to total protein and hemo- globin interferences in the assay. The element contains a porous spreading layer composed of a particulate structure. A fluorinated surfactant is also used in the assay. This surfactant has one or more fluorocarbon moieties provided, that when the surfactant has more than one such moiety, they are substantially linear. The surfactant can be incor- porated in the element or added at the time of the assay.

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